RESUMO Objetivo: identificar, por meio de uma revisão de escopo, as categorias da Classificação Internacional de Funcionalidade, Incapacidade e Saúde descritas em estudos sobre as afasias. Métodos: foi realizada uma busca nas bases de dados EMBASE, LILACS, PubMed, Scopus e Web of Science e em quatro buscadores da literatura cinzenta a partir dos DECs, termos Mesh e termos livres relacionados à “International Classification of Functioning, Disability and Health” e à “aphasia”. As recomendações do PRISMA foram utilizadas. Os gerenciadores EndNote e Rayyan foram usados para remoção das duplicatas e para a leitura dos títulos, resumos e textos completos. Foram elegíveis os trabalhos que incluíam “afasia” e algum conceito da Classificação Internacional de Funcionalidade, Incapacidade e Saúde; publicados a partir de 2001. As informações registradas foram: tipo de estudo, nível de evidência, amostra, objetivos e categorias. Revisão de Literatura: foram localizados 1366 trabalhos nas bases de dados e 341 na literatura cinzenta. As categorias de primeiro nível mais descritas nos 13 estudos selecionados foram: Estruturas do Sistema Nervoso (Cérebro); Funções Mentais (Linguagem); Comunicação (Conversação); Apoio e Relacionamentos (Família Nuclear). Sexo e idade foram alguns dos Fatores Pessoais mais identificados. Conclusão: esta revisão fornece suporte para recomendar o uso da Classificação Internacional de Funcionalidade, Incapacidade e Saúde na atuação com pessoas com afasia.

ABSTRACT Purpose: to identify, through a scoping review, the categories of the International Classification of Functioning, Disability and Health described in studies on aphasia. Methods: the search was performed by DECs, MeSH terms and free terms related to the “International Classification of Functioning, Disability and Health” and “aphasia” in five databases, EMBASE, LILACS, PubMed, Scopus and Web of Science, and four search engines of grey literature. The PRISMA recommendations were used. EndNote and Rayyan managers were used to remove duplicates and read titles, abstracts and full studies. Papers that contained “aphasia” and some aspect from the International Classification of Functioning, Disability and Health were eligible, published from 2001. The data recorded were: type of study, level of evidence, sample, objectives and categories. Literature Review: 1,366 studies were located in the databases and 341 in the grey literature. The mostly described first level categories in the 13 selected studies were: Structures of the Nervous System (Brain); Mental Functions (Language); Communication (Conversation); Support and Relationships (Immediate Family). Gender and age were some of the most identified Personal Factors. Conclusion: this review provides support to the use of the International Classification of Functioning, Disability and Health for performance with people with aphasia.

Abstract Background: To determine the burden of Rheumatoid Arthritis (RA) on patients' work productivity and health related quality of life (HRQoL), and examine the influence of several exposure variables; to analyze the progression of RA over 1 year and its impact on work productivity and HRQoL. Methods: International multicenter prospective survey including patients in 18 centers in Argentina, Brazil, Colombia and Mexico with diagnosis of RA and aged between 21-55 years. The following standard questionnaires were completed at baseline and throughout a 1-year follow-up: WPAI:RA, WALS, WLQ-25, EQ-5D-3 L and SF-36. Clinical and demographic variables were also collected through interview. Results: The study enrolled 290 patients on baseline visit. Overall mean scores at baseline visit were: WPAI:RA (presenteeism) = 29.5% (SD = 28.8%); WPAI:RA (absenteeism) = 9.0% (SD = 23.2%); WPAI:RA (absenteeism and presenteeism) = 8.6% (SD = 22.6%); WALS = 9.0 (SD = 6.1); WLQ-25 = 7.0% (SD = 5.1%); SF-36 Physical Scale = 39.1 (SD = 10.3) and Mental Scale = 45.4 (SD = 11.3); EQ-5D-3 L VAS = 69.8 (SD = 20.4) and EQ-5D-3 L index = 0.67 (SD = 0.23). Higher educational levels were associated with better results in WLQ-25, while previous orthopedic surgeries reduced absenteeism results of WPAI:RA and work limitations in WLQ-25. Higher disease duration was associated with decreased HRQoL. Intensification of disease activity was associated with decreased work productivity and HRQoL, except in WLQ-25. In the longitudinal analysis, worsening in disease activity was associated with a decrease in both work productivity and HRQoL. Conclusions: RA patients are dealing with workplace disabilities and limitations and loss in HRQoL, and multiple factors seems to be associated with this. Worsening of disease activity further decreased work productivity and HRQoL, stressing the importance of disease tight control.

ABSTRACT Tooth bleaching is a technique of choice to obtain a harmonious smile, but bleaching agents may damage the dental pulp. Objective: This study evaluated the inflammatory responses of human dental pulp after the use of two bleaching techniques. Material and Methods: Pulp samples were collected from human third molars extracted for orthodontic reasons and divided into three groups: control - no tooth bleaching (CG) (n=7); at-home bleaching with 15% carbamide peroxide (AH) (n = 10), and in-office bleaching with 38% hydrogen peroxide (IO) (n=12). Pulps were removed and stained with hematoxylin-eosin for microscopic analysis of inflammation intensity, collagen degradation, and pulp tissue organization. Immunohistochemistry was used to detect mast cells (tryptase+), blood vessels (CD31+), and macrophages (CD68+). Chi-square, Kruskal-Wallis, and Mann Whitney tests were used for statistical analysis. The level of significance was set at p<.05. Results: The inflammation intensity and the number of macrophages were significantly greater in IO than in AH and CG (p<0.05). The results of CD31+ (blood vessels per mm2) were similar in CG (61.39±20.03), AH (52.29±27.62), and IO (57.43±8.69) groups (p>0.05). No mast cells were found in the pulp samples analyzed. Conclusion: In-office bleaching with 38% hydrogen peroxide resulted in more intense inflammation, higher macrophages migration, and greater pulp damage then at-home bleaching with 15% carbamide peroxide, however, these bleaching techniques did not induce migration of mast cells and increased the number of blood vessels.

The phytochemical investigation of the flowers of Pterogyne nitens (Caesalpinioideae) resulted in the isolation and identification of nine phenolic derivatives, quercetin 3-O-sophoroside, taxifolin, astilbin, ourateacatechin, caffeic, ferulic, sinapic, chlorogenic and gallic acid, besides two guanidine alkaloids, pterogynine, pterogynidine. This is the first time these compounds have been reported in P. nitens flowers. As this is a monospecific genus, these secondary metabolites may have taxonomical significance. Their structures were assigned on the basis of spectroscopic analyses, including two-dimensional NMR techniques.

Este artigo apresenta o processo de avaliação de um material educativo, o jogo ZIG-ZAIDS, que teve por objetivo verificar a aplicabilidade deste material em espaços educacionais formais e informais, ou seja, investigar como vem sendo utilizado por profissionais e pais, e pela população-alvo (pré-adolescentes). O estudo envolveu o envio de questionários de avaliação a escolas e instituições que faziam uso do jogo, entrevistas, visitas a alguns locais onde o jogo estava em uso e testagem com grupos de alunos. Incluiu ainda análise de avaliações enviadas anteriormente pelas autoras a solicitantes do jogo. Os resultados demonstraram que o nível de informação da população é mais relevante do que a idade em relação ao impacto do jogo. Outro aspecto destacado relaciona-se à aplicabilidade do ZIG-ZAIDS a situações diversas, como: em treinamentos de profissionais de ensino e saúde; em atividades com menores que vivem na rua; em eventos de prefeituras e instituições, em escolas, empresas, comunidades e postos de saúde. Sintetizando, o ZIG-ZAIDS foi considerado uma alternativa lúdica, criativa e inovadora para informar sobre AIDS e sexualidade.

This article presents the evaluation process for the ZIG-ZAIDS game, investigating the material's applicability in formal and informal educational contexts, i.e., how the game has been used by health professionals, parents, and the target population (pre-adolescents, or children over 9 years old). The study involved evaluation questionnaires sent to a list of schools and institutions using the game, plus interviews and visits to places where the game was used as well as tested with groups of students. It also includes an analysis of evaluation previously sent by the authors to people who had requested the game. The results showed that the population's level of information is more relevant than age in relation to the game's impact. Another important aspect relates to ZIG-ZAIDS' applicability to different situations: training of health and teaching professionals; activities with street children; municipal institutions and events, schools, companies, communities, and health care centers. In summary, ZIG-ZAIDS was found to be an entertaining, creative, and innovative alternative for providing information on AIDS and sexuality.

Este artigo apresenta o processo de avaliação de um material educativo, o jogo ZIG-ZAIDS, que teve por objetivo verificar a aplicabilidade deste material em espaços educacionais formais e informais, ou seja, investigar como vem sendo utilizado por profissionais e pais, e pela população-alvo (pré-adolescentes). O estudo envolveu o envio de questionários de avaliação a escolas e instituições que faziam uso do jogo, entrevistas, visitas a alguns locais onde o jogo estava em uso e testagem com grupos de alunos. Incluiu ainda análise de avaliações enviadas anteriormente pelas autoras a solicitantes do jogo. Os resultados demonstraram que o nível de informação da população é mais relevante do que a idade em relação ao impacto do jogo. Outro aspecto destacado relaciona-se à aplicabilidade do ZIG-ZAIDS a situações diversas, como: em treinamentos de profissionais de ensino e saúde; em atividades com menores que vivem na rua; em eventos de prefeituras e instituições, em escolas, empresas, comunidades e postos de saúde. Sintetizando, o ZIG-ZAIDS foi considerado uma alternativa lúdica, criativa e inovadora para informar sobre AIDS e sexualidade.

This article presents the evaluation process for the ZIG-ZAIDS game, investigating the material's applicability in formal and informal educational contexts, i.e., how the game has been used by health professionals, parents, and the target population (pre-adolescents, or children over 9 years old). The study involved evaluation questionnaires sent to a list of schools and institutions using the game, plus interviews and visits to places where the game was used as well as tested with groups of students. It also includes an analysis of evaluation previously sent by the authors to people who had requested the game. The results showed that the population's level of information is more relevant than age in relation to the game's impact. Another important aspect relates to ZIG-ZAIDS' applicability to different situations: training of health and teaching professionals; activities with street children; municipal institutions and events, schools, companies, communities, and health care centers. In summary, ZIG-ZAIDS was found to be an entertaining, creative, and innovative alternative for providing information on AIDS and sexuality.